- Nucleic acid electrophoresis is a commonly used molecular biology technique for separating and analyzing DNA and RNA molecules. It is based on the principle that nucleic acid molecules migrate at different speeds in an electric field, and the nucleic acid samples are separated into different band profiles by electrophoresis instruments, thus realizing qualitative and quantitative analysis of nucleic acid molecules. This article will introduce the principle of nucleic acid electrophoresis and common electrophoresis methods.
- With the outbreak of the COVID-19, scientists around the world have rapidly embarked on vaccine development. Among them, mRNA vaccines have become an emerging vaccine technology that has attracted much attention. In this paper, we will introduce the development process and challenges of mRNA vaccines.
- Ribonuclease inhibitor (RI) is a large (~450 residues, ~49 kDa), acidic (pI ~4.7), leucine-rich repeat protein that forms extremely tight complexes with certain ribonucleases.
- Viruses are microorganisms that have attracted widespread attention in the biological community
- DNA, known as Deoxyribonucleic Acid, is a bio-molecule found in cells and the main carrier of an organism's genetic information.
- The year 2023 marks the 70th anniversary of the discovery of the double-helix structure of DNA. On February 28, 1953, Watson and Crick succeeded in deducing a three-dimensional structural model of the genetic material DNA, based on X-ray diffraction photographs taken by the female scientist Franklin.
- Proteinase K is a powerful proteolytic enzyme isolated from Candida albicans, with high specific activity and is a key reagent for DNA extraction
- Lysozyme is an antibacterial enzyme with a molecular weight of 14.4kDa and is a member of the innate immune system.
- Agarose, abbreviated as AG, is an uncharged neutral component of agar, also translated as agarose.